Linea 2 – Neuroimmunopatologia e neuroinfiammazione

L’Episcopo F, Tirolo C, Testa N, Caniglia S, Morale MC, Cossetti C, D’Adamo P, Zardini E, Andreoni L, Ihekwaba AE, Serra PA, Franciotta D, Martino G, Pluchino S, Marchetti B.Reactive astrocytes and Wnt/ -catenin signaling link nigrostriatal injury to repair in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson’s disease. Neurobiol Dis 2011; 41(2): 508-27

Benedetti L, Briani C, Franciotta D, Fazio R, Paolasso I, Comi C, Luigetti M, Sabatelli M, Giannini F, Mancardi GL, Schenone A, Nobile-Orazio E, Cocito D. Rituximab in patients with chronic inflammatory demyelinating polyradiculoneuropathy: a report of 13 cases and review of the literature. J Neurol Neurosurg Psychiatry 2011; 82(3):306-8

Franciotta D, Di Stefano AL, Jarius S, Zardini E, Tavazzi E, Ballerini C, Marchioni E, Bergamaschi R, Ceroni M. Cerebrospinal BAFF and Epstein-Barr virus-specific oligoclonal bands in multiple sclerosis and other inflammatory demyelinating neurological diseases. J Neuroimmunol 2011; 230(1-2):160-3

Piccolo G, Cortese A, Tavazzi E, Piccolo L, Sassone J, Ciammola A, Alfonsi E, Colombo I, Moggio M. Late onset oculopharyngeal muscular dystrophy with prominent neurogenic features and short GCG trinucleotide expansion. Muscle Nerve 2011; 43(1):141-2

Govoni S, Pascale A, Amadio M, Calvillo L, D’Elia E, Cereda C, Fantucci P, Ceroni M, Vanoli E. NGF and Heart: IS THERE A ROLE in heart disease? Pharmacol Res 2011; 63(4):266-77

Tavazzi E, Magrassi L, Maccabruni A, Bargiggia V, Pichiecchio A, Delbue S, Ferrante P, Minoli L, Marchioni E. Acute transient inflammatory leukoencephalopathy in HIV. Neurol Sci 2011; 32(5):899-902

Ghezzi A, Grimaldi LM, Marrosu MG, Pozzilli C, Comi G, Bertolotto A, Trojano M, Gallo P, Capra R, Centonze D, Millefiorini E, Sotgiu S, Brescia Morra V, Amato MP, Lugaresi A, Mancardi G, Caputo D, Montanari E, Provinciali L, Durelli L, Bergamaschi R, Bellantonio P, Tola MR, Cottone S, Savettieri G, Tedeschi G. Natalizumab therapy of multiple sclerosis: recommendations of the Multiple Sclerosis Study Group-Italian Neurological Society. Neurol Sci 2011; 32(2):351-8

Bergamaschi R. Are nonintestinal inflammatory diseases and celiac disease linked? Hepat Mon. 2011;11(1):40

Franciotta D, Zardini E, Caporali R, Piccolo L, Alberici E, Romani A, Bergamaschi R, Marchioni E, Ceroni M, Piccolo G. Systemic sclerosis in aquaporin-4 antibody-positive longitudinally extensive transverse myelitis. J Neurol Sci 2011; 303(1-2):139-41

Piccolo G, Tavazzi E, Jarius S, Alfonsi E, Cavagna L, Piccolo L, Zardini E, Voltz R,Franciotta D. Anti-Ma2/Ta antibodies in a woman with primary lateral sclerosis-like phenotype and Sjögren syndrome. Neurol Sci 2011; 32(5):915-7

Marchioni E, Tavazzi E, Franciotta D. ADEM as a niche variant of post infectious neurological syndromes. Neuroimmunol 2011; 236(1-2):123

Zucchella C, Sinforiani E, Tavazzi E, Del Bue S, Novati S, Maserati R, Ceroni M, Bastianello S, Minoli L, Ferrante P, Marchioni E. Neuropsychological evaluation and follow up in jcv- and non-jcv-related leukoencephalopathies in HIV infection. Neurol Sci 2011; 32(5):833-9

Rotondi M, Stufano F, Lagonigro MS, La Manna L, Zerbini F, Ghilotti S, Pagliari MT, Coperchini F, Magri F, Bergamaschi R, Oliviero A, Chiovato L. Interferon- but not Glatiramer acetate stimulates CXCL10 secretion in primary cultures of thyrocytes: A clue for understanding the different risks of thyroid dysfunctions in patients with multiple sclerosis treated with either of the two drugs. J Neuroimmunol 2011; 234(1-2):161-4

Jarius S, Paul F, Franciotta D, Ruprecht K, Ringelstein M, Bergamaschi R, Rommer P, Kleiter I, Stich O, Reuss R, Rauer S, Zettl UK, Wandinger KP, Melms A, Aktas O, Kristoferitsch W, Wildemann B. Cerebrospinal fluid findings in aquaporin-4 antibody positive neuromyelitis optica: Results from 211 lumbar punctures. J Neurol Sci 2011; 306(1-2):82-90

Jarius S, Jacobi C, de Seze J, Zephir H, Paul F, Franciotta D, Rommer P, Mader S, Kleiter I, Reindl M, Akman-Demir G, Seifert-Held T, Kristoferitsch W, Melms A, Wandinger KP, Wildemann B. Frequency and syndrome specificity of antibodies to aquaporin-4 in neurological patients with rheumatic disorders. Mult Scler 2011; 17(9):1067-73

Patti F, Amato M, Trojano M, Bastianello S, Tola M, Picconi O, Cilia S, Cottone S, Centonze D, Gasperini C. Quality of life, depression and fatigue in mildly disabled patients with relapsing-remitting multiple sclerosis receiving subcutaneous interferon beta-1a: 3-year results from the COGIMUS (COGnitive Impairment in Multiple Sclerosis) study. Mult Scler 2011; 17(8):991-1001

Sawcer S, Hellenthal G, Pirinen M, Spencer CC, Patsopoulos NA, Moutsianas L, Dilthey A, Su Z, Freeman C, Hunt SE, Edkins S, Gray E, Booth DR, Potter SC, Goris A, Band G, Oturai AB, Strange A, Saarela J, Bellenguez C, Fontaine B, Gillman M, Hemmer B, Gwilliam R, Zipp F, Jayakumar A, Martin R, Leslie S, Hawkins S, Giannoulatou E, D’alfonso S, Blackburn H, Boneschi FM, Liddle J, Harbo HF, Perez ML, Spurkland A, Waller MJ, Mycko MP, Ricketts M, Comabella M, Hammond N, Kockum I, McCann OT, Ban M, Whittaker P, Kemppinen A, Weston P, Hawkins C, Widaa S, Zajicek J, Dronov S, Robertson N, Bumpstead SJ, Barcellos LF, Ravindrarajah R, Abraham R, Alfredsson L, Ardlie K, Aubin C, Baker A, Baker K, Baranzini SE, Bergamaschi L, Bergamaschi R, Bernstein A, Berthele A, Boggild M, Bradfield JP, Brassat D, Broadley SA, Buck D, Butzkueven H, Capra R, Carroll WM, Cavalla P, Celius EG, Cepok S, Chiavacci R, Clerget-Darpoux F, Clysters K, Comi G, Cossburn M, Cournu-Rebeix I, Cox MB, Cozen W, Cree BA, Cross AH, Cusi D, Daly MJ, Davis E, de Bakker PI, Debouverie M, D’hooghe MB, Dixon K, Dobosi R, Dubois B, Ellinghaus D, Elovaara I, Esposito F, Fontenille C, Foote S, Franke A, Galimberti D, Ghezzi A, Glessner J, Gomez R, Gout O, Graham C, Grant SF, Guerini FR, Hakonarson H, Hall P, Hamsten A, Hartung HP, Heard RN, Heath S, Hobart J, Hoshi M, Infante-Duarte C, Ingram G, Ingram W, Islam T, Jagodic M, Kabesch M, Kermode AG, Kilpatrick TJ, Kim C, Klopp N, Koivisto K, Larsson M, Lathrop M, Lechner-Scott JS, Leone MA, Leppä V, Liljedahl U, Bomfim IL, Lincoln RR, Link J, Liu J, Lorentzen AR, Lupoli S, Macciardi F, Mack T, Marriott M, Martinelli V, Mason D, McCauley JL, Mentch F, Mero IL, Mihalova T, Montalban X, Mottershead J, Myhr KM, Naldi P, Ollier W, Page A, Palotie A, Pelletier J, Piccio L, Pickersgill T, Piehl F, Pobywajlo S, Quach HL, Ramsay PP, Reunanen M, Reynolds R, Rioux JD, Rodegher M, Roesner S, Rubio JP, Rückert IM, Salvetti M, Salvi E, Santaniello A, Schaefer CA, et all Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.Nature 2011; 476(7359):214-9

Benedetti L, Zardini E, Briani C, Beronio A, Gastaldi S, Jarius S, Mancardi GL, Schenone A,Franciotta D. B-cell-activating factor in rituximab-treated patients with anti-MAG polyneuropathy. J Neurol Neurosurg Psychiatry 2011; 82(11):1291-4

Portaccio E, Ghezzi A, Hakiki B, Martinelli V, Moiola L, Patti F, La Mantia L, Mancardi GL, Solaro C, Tola MR, Pozzilli C, De Giglio L, Totaro R, Lugaresi A, De Luca G, Paolicelli D, Marrosu MG, Comi G, Trojano M, Amato MP; MS Study Group of the Italian Neurological Society (Amato MP, Portaccio E, Hakiki B, Zipoli V, Siracusa G, Ghezzi A, Rizzo A, Zaffaroni M, Martinelli V, Radaelli M, Moiola L, Comi G, Milanese C, La Mantia L, Protti A, Spreafico C, Marazzi R, Cavalla P, Masera S, Bergamaschi R, Mancardi G, Capello E, Solaro C, Molinari F, Tola MR, Caniatti L, Granella F, Immovilli P, Annunziata P, De Santi L, Plewnia K, Guidi L, Bartolozzi ML, Mazzoni M, Pozzilli C, De Giglio L, Totaro R, Carolei A, Lugaresi A, De Luca G, Di Tommaso V, Trojano M, Paolicelli D, Carrozzo A, D’Onghia M, Marrosu MG, Musu L, Patti F, Cavallaro T, Lo Fermo S). Breastfeeding is not related to postpartum relapses in multiple sclerosis. Neurology. 2011 Jul 12;77(2):145-50

Khatri B, Barkhof F, Comi G, Hartung HP, Kappos L, Montalban X, Pelletier J, Stites T, Wu S, Holdbrook F, Zhang-Auberson L, Francis G, Cohen JA, (in witch Bergamaschi R).Comparison of fingolimod with interferon beta-1a in relapsing-remitting multiple sclerosis: a randomised extension of the TRANSFORMS study. Lancet Neurol 2011 Jun;10(6):520-9

Paul O’Connor, M.D., Jerry S. Wolinsky, M.D., Christian Confavreux, M.D., Giancarlo Comi, M.D., Ludwig Kappos, M.D., Tomas P. Olsson, M.D., Ph.D., Hadj Benzerdjeb, M.D., Philippe Truffinet, M.D., Lin Wang, Ph.D., Aaron Miller, M.D., and Mark S. Freedman, M.D. for the TEMSO Trial Group (Cosi V). Randomized Trial of Oral Teriflunomide for Relapsing Multiple Sclerosis N Engl J Med 2011; 365:1293-1303

Bastianello S, Giugni E, Amato MP, Tola MR, Trojano M, Galletti S, Luccichenti G, Quarantelli M, Picconi O, Patti F, Study Group TC. Changes in magnetic resonance imaging disease measures over 3 years in mildly disabled patients with relapsing-remitting multiple sclerosis receiving interferon beta-1a in the COGnitive Impairment in MUltiple Sclerosis (COGIMUS) study. BMC Neurol 2011; 11(1):125

Bastianello S, Romani A, Viselner G, Colli Tibaldi E, Giugni E, Altieri M, Cecconi P, Mendozzi L, Farina M, Mariani D, Galassi A, Quattrini C, Mancini M, Bresciamorra V, Lagace A, McDonald S, Bono G, Bergamaschi R. Chronic Cerebrospinal Venous Insufficiency in Multiple Sclerosis: Clinical Correlates from a Multicentre Study. BMC Neurol 2011; 11(1):132

Tavazzi E, Ferrante P, Khalili K . Progressive multifocal leukoencephalopathy: an unexpected complication of modern therapeutic monoclonal antibody therapies. Clin Microbiol Infect 2011; 17(12):1776-80

Teunissen CE, Tumani H, Bennett JL, Berven FS, Brundin L, Comabella M, Franciotta D, Federiksen JL, Fleming JO, Furlan R, Hintzen RQ, Hughes SG, Jimenez CR, Johnson MH, Killestein J, Krasulova E, Kuhle J, Magnone MC, Petzold A, Rajda C, Rejdak K, Schmidt HK, van Pesch V, Waubant E, Wolf C, Deisenhammer F, Giovannoni G, Hemmer B. Consensus Guidelines for CSF and Blood Biobanking for CNS Biomarker Studies. Mult Scler Int 2011; 2011:246412

Martinelli V, Cocco E, Capra R, Salemi G, Gallo P, Capobianco M, Pesci I, Ghezzi A, Pozzilli C, Lugaresi A, Bellantonio P, Amato MP, Grimaldi LM, Trojano M, Mancardi GL, Bergamaschi R, Gasperini C, Rodegher M, Straffi L, Ponzio M, Comi G. Acute myeloid leukemia in Italian patients with multiple sclerosis treated with mitoxantrone. Neurology 2011; 77(21):1887-95

Linea 3 – Processi neurodegenerativi e disordini del movimento

Zoccolella S, Savarese M, Lamberti P, Manni R, Pacchetti C, Logroscino G. Sleep disorders and the natural history of Parkinson’s disease: The contribution of epidemiological studies. Sleep Med Rev 2011; 15(1):41-50

Martignoni E, Citterio A, Zangaglia R, Godi L, Pacchetti C, Fundarò C, Corengia E, Bono G, Nappi G. How parkinsonism influences life: the patients’ point of view. Neurol Sci 2011; 32:125-131

Corrado L, Gagliardi S, Carlomagno Y, Mennini T, Ticozzi N, Mazzini L, Silani V, Cereda C, D’Alfonso S. VPS54 genetic analysis in ALS Italian cohort. Eur J Neurol 2011; 18(4):e41-e42

Gagliardi S, Ogliari P, Davin A, Corato M, Cova E, Abel K, Cashman JR, Ceroni M, Cereda C. Flavin-Containing Monooxygenase mRNA Levels are Up-Regulated in ALS Brain Areas in SOD1-Mutant Mice. Neurotox Res 2011; 20(2):150-8

Rondanelli M, Opizzi A, Monteferrario F, Antoniello N, Manni R, Klersy C. The Effect of Melatonin, Magnesium, and Zinc on Primary Insomnia in Long-Term Care Facility Residents in Italy: A Double-Blind, Placebo-Controlled Clinical Trial. J Am Geriatr Soc 2011; 59(1):82-90

Matrisciano F, Busceti CL, Bucci D, Orlando R, Caruso A, Molinaro G, Cappuccio I, Riozzi B, Gradini R, Motolese M, Caraci F, Copani A, Scaccianoce S, Melchiorri D, Bruno V, Battaglia G, Nicoletti F. Induction of the wnt antagonist dickkopf-1 is involved in stress-induced hippocampal damage. PLoS One 2011; 6(1):e16447

Balducci C, Mehdawy B, Mare L, Giuliani A, Lorenzini L, Sivilia S, Giardino L, Calzà L, Lanzillotta A, Sarnico I, Pizzi M, Usiello A, Viscomi AR, Ottonello S, Villetti G, Imbimbo BP, Nisticò G, Forloni G, Nisticò R. The -Secretase Modulator CHF5074 Restores Memory and Hippocampal Synaptic Plasticity in Plaque-Free Tg2576 Mice. J Alzheimers Dis 2011; 24(4):799-816

Cortese A, Zangaglia R, Lozza A, Piccolo G, Pacchetti C. Copper deficiency in Wilson’s disease: Peripheral neuropathy and myelodysplastic syndrome complicating zinc treatment. Mov Disord 2011; 26(7):1361-2

Milani P, Gagliardi S, Cova E, Cereda C. SOD1 Transcriptional and Posttranscriptional Regulation and Its Potential Implications in ALS. Neurol Res Int 2011; (–):458427

Fumagalli M, Giannicola G, Rosa M, Marceglia S, Lucchiari C, Mrakic-Sposta S, Servello D,Pacchetti C, Porta M, Sassi M, Zangaglia R, Franzini A, Albanese A, Romito L, Piacentini S, Zago S, Pravettoni G, Barbieri S, Priori A. Conflict-dependent dynamic of subthalamic nucleus oscillations during moral decisions. Soc Neurosci 2011; 6(3):243-56

Armentero MT, Levandis G, Bazzini E, Cerri S, Ghezzi C, Blandini F. Adhesion molecules as potential targets for neuroprotection in a rodent model of Parkinson’s disease. Neurobiol Dis 2011; 43(3):663-8

Sinforiani E, Zucchella C, Pasotti C, Casoni F, Bini P, Costa A. The effects of alcohol on cognition in the elderly: from protection to neurodegeneration. Funct Neurol 2011; The effects of alcohol on cognition in the elderly: from protection to neurodegeneration. Funct Neurol 2011; 26 (2): 103-6

Rosa M, Giannicola G, Servello D, Marceglia S, Pacchetti C, Porta M, Sassi M, Scelzo E, Barbieri S, Priori A. Subthalamic Local Field Beta Oscillations during Ongoing Deep Brain Stimulation in Parkinson’s Disease in Hyperacute and Chronic Phases. Neurosignals 2011; 19(3):151-62

Berliocchi L, Ciociaro A, Russo R, Cassiano MG, Blandini F, Rotiroti D, Morrone LA, Corasaniti MT. Toxic profile of bergamot essential oil on survival and proliferation of SH-SY5Y neuroblastoma cells. Food Chem Toxicol 2011; 49: 2780-92

Melcangi RC, Caruso D, Levandis G, Abbiati F, Armentero MT, Blandini F.  Modifications of Neuroactive Steroid Levels in an Experimental Model of Nigrostriatal Degeneration: Potential Relevance to the Pathophysiology of Parkinson’s Disease. J Mol Neurosci 2011

Del Bo R, Tiloca C, Pensato V, Corrado L, Ratti A, Ticozzi N, Corti S, Castellotti B, Mazzini L, Sorarù G, Cereda C, D’Alfonso S, Gellera C, Comi GP, Silani V. Novel optineurin mutations in patients with familial and sporadic amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry 2011; 82(11):1239-1243

Manni R, Terzaghi M, Ratti PL, Repetto A, Zangaglia R, Pacchetti C.Hallucinations and REM sleep behaviour disorder in Parkinson’s disease: Dream imagery intrusions and other hypotheses. Conscious Cogn 2011; 20(4):1021-6

Armentero MT, Pinna A, Ferré S, Lanciego JL, Müller CE, Franco R. Past, present and future of A(2A) adenosine receptor antagonists in the therapy of Parkinson’s disease. Pharmacol Ther 2011; 132: 280-99

Beghi E, Pupillo E, Messina P, Giussani G, Chiò A, Zoccolella S, Moglia C, Corbo M, Logroscino G, (in wich Cereda  C, Ceroni M, Citterio A). Coffee and Amyotrophic Lateral Sclerosis: A Possible Preventive Role. Am J Epidemiol 2011; 174(9):1002-8

Linea 4 - Neurologia e psichiatria dello sviluppo

Cagliani R, Fruguglietti ME, Berardinelli A, D’Angelo MG, Prelle A, Riva S, Gorni K, Orcesi S, Lamperti C, Pichiecchio A, Signaroldi E, Tupler R, Magri F, Govoni A, Corti S, Bresolin N, Moggio M, Comi GP. New molecular findings in congenital myopathies due to selenoprotein N gene mutations. J Neurol Sci 2011; 300(1-2):107-13

Gargiulo A, Testa F, Rossi S, Di Iorio V, Fecarotta S, de Berardinis T, Iovine A, Magli A,Signorini S, Fazzi E, Galantuomo MS, Fossarello M, Montefusco S, Ciccodicola A, Neri A, Macaluso C, Simonelli F, Surace EM. Molecular and clinical characterization of albinism in a large cohort of Italian patients. Invest Ophthalmol Vis Sci 2010; 52(3):1281-9

Termine C, Selvini C, Balottin U, Luoni C, Eddy CM, Cavanna AE. Self-, parent-, and teacher-reported behavioral symptoms in youngsters with Tourette syndrome: A case-control study. Eur J Paediatr Neurol 2011; 15(2):95-100

Fazzi E, Signorini SG, Bomba M, Luparia A, Lanners J, Balottin U. Reach on sound: A key to object permanence in visually impaired children. Early Hum Dev 2011; 87(4):289-96

Carlson C, Teutonico etc. Bilateral invasive electroencephalography in patients with tuberous sclerosis complex: a path to surgery. J Neurosurg Pediatrics 7:000-000, 2011

Orcesi S, La Piana R, Uggetti C, Tonduti D, Pichiecchio A, Pasin M, Viselner G, Comi GP, Del Bo R, Ronchi D, Bastianello S, Balottin U. Spinal Cord Calcification in an Early-Onset Progressive Leukoencephalopathy. J Child Neurol 2011; 26(7):876-80

Pichiecchio A, Di Perri C, Arnoldi S, Berardinelli A, Branca V, Balottin U, Bastianello S. Cerebellum enlargement and corpus callosum agenesis: a longitudinal case report. J Child Neurol 2011; 26(6):756-60

Mazzone E, Vasco G, Sormani MP, Torrente Y, Berardinelli A, Messina S, D’Amico A, Doglio L, Politano L, Cavallaro F, Frosini S, Bello L, Bonfiglio S, Zucchini E, De Sanctis R, Scutifero M, Bianco F, Rossi F, Motta MC, Sacco A, Donati MA, Mongini T, Pini A, Battini R, Pegoraro E, Pane M, Gasperini S, Previtali S, Napolitano S, Martinelli D, Bruno C, Vita G, Comi G, Bertini E, Mercuri E. Functional changes in Duchenne muscular dystrophy: A 12-month longitudinal cohort study. Neurology 2011; 77(3):250-6

Ronchi D, Cosi A, Tonduti D, Orcesi S, Bordoni A, Fortunato F, Rizzuti M, Sciacco M, Collotta M, Cagdas S, Capovilla G, Moggio M, Berardinelli A, Veggiotti P, Comi GP. Clinical and molecular features of an infant patient affected by Leigh Disease associated to m.14459G>A mitochondrial DNA mutation: a case report. BMC Neurol 2011; 11(1):85

Orcesi S, La Piana R, Comi G Response to correspondence on “spinal cord calcification in an early-onset progressive leukoencephalopathy”. J Child Neurol 2011; 26(8):1058

Facchin P, Rosa-Rizzotto M, Visonà Dalla Pozza L, Turconi AC, Pagliano E, Signorini S, Tornetta L, Trabacca A, Fedrizzi E. Multisite Trial Comparing the Efficacy of Constraint-Induced Movement Therapy with that of Bimanual Intensive Training in Children with Hemiplegic Cerebral Palsy: Postintervention Results. Am J Phys Med Rehabil 2011; 90(7):539-53

Pulliero A, Fazzi E, Cartiglia C, Orcesi S, Balottin U, Uggetti C, La Piana R, Olivieri I, Galli J, Izzotti A . The Aicardi-Goutières syndrome. Molecular and clinical features of RNAse deficiency and microRNA overload. Mutat Res 2011; 717(1-2):99-108

Linea 5 – Neurologia funzionale e disordini dei comportamenti adattativi

Sandrini G, Friberg L, Coppola G, Jänig W, Jensen R, Kruit M, Rossi P, Russell D, Sanchez Del Rìo M, Sand T, Schoenen J. Neurophysiological tests and neuroimaging procedures in non-acute headache (2nd edition). Eur J Neurol 2011; 18(3):373-381

Rossi P, Faroni JV, Nappi G. Short-term effectiveness of simple advice as a withdrawal strategy in simple and complicated medication overuse headache. Eur J Neurol 2010; 18(3): 396-401

Cazzola R, Rondanelli M, Trotti R, Cestaro B. Effects of weight loss on erythrocyte membrane composition and fluidity in overweight and moderately obese women. J Nutr Biochem 2011; 22(4):388-92

Greco R, Meazza C, Mangione AS, Allena M, Bolla M, Amantea D, Mizoguchi H,Sandrini G, Nappi G, Tassorelli C. Temporal profile of vascular changes induced by systemic nitroglycerin in the meningeal and cortical districts. Cephalalgia 2011; 31(2):190-8

Greco R, Mangione AS, Amantea D, Bagetta G, Nappi G, Tassorelli C. IkappaB-alpha expression following transient focal cerebral ischemia is modulated by nitric oxide. Brain Res 2011; 1372(–):145-51

Mancia G, Rosei EA, Ambrosioni E, Avino F, Carolei A, Daccò M, Di Giacomo G, Ferri C, Grazioli I, Melzi G, Nappi G, Pinessi L, Sandrini G, Trimarco B, Zanchin G. Hypertension and migraine comorbidity: prevalence and risk of cerebrovascular events: evidence from a large, multicenter, cross-sectional survey in Italy (MIRACLES study). J Hypertens 2011; 29(2):309-318

Perrotta A, Serrao M, Tassorelli C, Arce-Leal N, Guaschino E, Sances G, Rossi P, Bartolo M, Pierelli F, Sandrini G, Nappi G. Oral nitric-oxide donor glyceryl-trinitrate induces sensitization in spinal cord pain processing in migraineurs: A double-blind, placebo-controlled, cross-over study. Eur J Pain 2010; 15(5):482-90

Antonaci F, Nappi G, Galli F, Manzoni GC, Calabresi P, Costa A. Migraine and psychiatric comorbidity: a review of clinical findings. J Headache Pain 2011; 12:115-25

De Sanctis S, Grieco GS, Breda L, Casali C, Nozzi M, Del Torto M, Chiarelli F, Verrotti A. Prolonged Sporadic Hemiplegic Migraine Associated With a Novel De Novo Missense ATP1A2 Gene Mutation. Headache 2011; 51(3):447-50

Nappi RE, Sances G, Allais G, Terreno E, Benedetto C, Vaccaro V, Polatti F, Facchinetti F. Effects of an estrogen-free, desogestrel-containing oral contraceptive in women with migraine with aura: a prospective diary-based pilot study. Contraception 2011; 83(3): 223-8

Greco R, Mangione AS, Sandrini G, Maccarrone M, Nappi G, Tassorelli C. Effects of anandamide in migraine: data from an animal model. J Headache Pain 2011; 12(2):177-83

Ferrante E, Tassorelli C, Rossi P, Lisotto C, Nappi G. Focus on the management of thunderclap headache: from nosography to treatment. J Headache Pain 2011; 12(2):251-8

Rossi P, Vollono C, Valeriani M, Sandrini G. The contribution of clinical neurophysiology to the comprehension of the tension-type headache mechanisms. Clin Neurophysiol 2011; 122(6):1075-85

von Brevern M, Baloh RW, Bisdorff A, Brandt T, Bronstein AM, Furman JM, Goadsby PJ, Neuhauser H, Radtke A, Versino M. Response to: Migraine and Vertigo: A Marriage of Convenience? Headache 2011; 51(2): 308-9

Balottin U, Chiappedi M, Rossi M, Termine C, Nappi G. Childhood and adolescent migraine: A neuro-psychiatric disorder? Med Hypotheses 2011; 76(6):778-81

Sandrini G, Perrotta A, Tassorelli C, Torelli P, Brighina F, Sances G, Nappi G. Botulinum toxin type-A in the prophylactic treatment of medication-overuse headache: a multicenter, double-blind, randomized, placebo-controlled, parallel group study. J Headache Pain 2011; 12(4):427-33

Bartolini M, Giamberardino MA, Lisotto C, Martelletti P, Moscato D, Panascia B, Savi L, Pini LA, Sances G, Santoro P, Zanchin G, Omboni S, Ferrari MD, Brighina F, Fierro B. A double-blind, randomized, multicenter, Italian study of frovatriptan versus almotriptan for the acute treatment of migraine. J Headache Pain 2011; 12(3):361-8

Nappi RE, Albani F, Sances G, Terreno E, Brambilla E, Polatti F. Headaches During Pregnancy. Curr Pain Headache Rep 2011; 15(4):289-94

Munksgaard SB, Allena M, Tassorelli C, Rossi P, Katsarava Z, Bendtsen L, Nappi G, Jensen R. What do the patients with medication overuse headache expect from treatment and what are the preferred sources of information? J Headache Pain 2011; 12(1): 91-6

Galli F, Pozzi G, Frustaci A, Allena M, Anastasi S, Chirumbolo A, Ghiotto N, Guidetti V, Matarrese A, Nappi G, Pazzi S, Quartesan R, Sances G, Tassorelli C. Differences in the Personality Profile of Medication-Overuse Headache Sufferers and Drug Addict Patients: A Comparative Study Using MMPI-2. Headache 2011; 51(8):1212-27

Moschiano F, D’Amico D, Canavero I, Pan I, Micieli G, Bussone G. Migraine and depression: common pathogenetic and therapeutic ground? Neurol Sci 2011; 32 Suppl 1(–):S85-8

Andrée C, Stovner LJ, Steiner TJ, Barré J, Katsarava Z, Lainez JM, Lanteri-Minet M, Mick G, Rastenyte D, de la Torre ER, Tassorelli C, Vriezen P, Lampl C. The Eurolight project: the impact of primary headache disorders in Europe. Description of methods. J Headache Pain 2011; 12(5):541-9

Jensen R, Tassorelli C, Rossi P, Allena M, Osipova V, Steiner TJ, Sandrini G, Olesen J,Nappi G. A basic diagnostic headache diary (BDHD) is well accepted and useful in the diagnosis of headache. A multicentre European and Latin American study. Cephalalgia 2011; 31(15):1549-60

Nappi G, Moskowitz MA. Cluster headache and trigeminal autonomic cephalalgias general aspects. Handb Clin Neurol 2011; 97: 387-8 Netherlands

Nappi G, Sandrini G. Other primary headaches – general aspects. Handb Clin Neurol 2011; 97(–):451 Netherlands

Buzzi MG, Tassorelli C. Experimental models of migraine. Handb Clin Neurol 2011; 97(–):109-23

Sances G, Catarci T. Management of headache patients. Handb Clin Neurol 2011; 97(–):127-35 Netherlands

Friberg L, Sandrini G, Perrotta A. Neuroimaging and clinical neurophysiology in cluster headache and trigeminal autonomic cephalalgias. Handb Clin Neurol 2011; 97(–): 413-20 Netherlands

Sandrini G, Rossi P. The clinical neurophysiology of tension-type headache. Handb Clin Neurol 2010; 97(-): 367-76 Netherlands

Manni R, Ghiotto N. Hypnic headache. Handb Clin Neurol 2011; 97(–): 469-72 Netherlands

Marchioni E, Minoli L. Headache attributed to infections nosography and differential diagnosis. Handb Clin Neurol 2011; 97 (–): 601-26 Netherlands

Strupp M, Versino M, Brandt T. Vestibular migraine. Handb Clin Neurol 2010; 97(–): 755-71 Netherlands

Schoenen J, Allena M, Magis D. Neurostimulation therapy in intractable headaches. Handb Clin Neurol 2011; 97(–): 443-50

Linea 6 – Neuroscienze intervenzionali e metodologie innovative in riabilitazione

Bartolo M, Zucchella C, Pichiecchio A, Pucci E, Sandrini G, Sinforiani E. Alien hand syndrome in left posterior stroke. Neurol Sci 2011; 32(3):483-6

Perrotta A, Sandrini G, Serrao M, Buscone S, Tassorelli C, Tinazzi M, Zangaglia R, Pacchetti C, Bartolo M, Pierelli F, Martignoni E. Facilitated temporal summation of pain at spinal level in Parkinson’s disease. Mov Disord 2010; 26(3):442-8

Vitali P, Dronkers N, Pincherle A, Giovagnoli AR, Marras C, D’Incerti L, Ghielmetti F, Spreafico R, Villani F. Accuracy of pre-surgical fMRI confirmed by subsequent crossed aphasia. Neurol Sci 2011; 32(1):175-80

Vitali P, Maccagnano E, Caverzasi E, Henry RG, Haman A, Torres-Chae C, Johnson DY, Miller BL, Geschwind MD. Diffusion-weighted MRI hyperintensity patterns differentiate CJD from other rapid dementias. Neurology 2011; 76(20):1711-9

Ranavolo A, Conte C, Iavicoli S, Serrao M, Silvetti A, Sandrini G, Pierelli F, Draicchio. F.Walking strategies of visually impaired people on trapezoidal- and sinusoidal-section tactile groundsurface indicators’. Ergonomics 2011; 54; 3: 246- 56

Serrao M, Di Fabio R, Bartolo M, Perrotta A, Tassorelli C, Coppola G, Davassi C, Padua L,Sandrini G, Pierelli F. The contribution of trigemino-cervical reflexes in distinguishing progressive supranuclear palsy from multiple system atrophy. Clin Neurophysiol 2011; 122(9):1812-5

Frati A, Pichierri A, Bastianello S, Raco A, Santoro A, Esposito V, Giangaspero F, Salvati M. Frameless Stereotactic Cerebral Biopsy: Our Experience in 296 Cases. Stereotact Funct Neurosurg 2011; 89(4):234-45

Ramat S, Nesti A, Versino M, Colnaghi S, Magnaghi C, Bianchi A, Beltrami G. A new device to assess static ocular torsion. Ann N Y Acad Sci 2011; 1233(1): 226-30

Versino M, Colnaghi S. Check your vestibular skills by reading about the rotational vertebral artery syndrome. Neurol Sci 2011; 32(6):1239-40

Colnaghi S, Ramat S, D’Angelo E, Cortese A, Beltrami G, Moglia A, Versino M. Theta-Burst Stimulation of the Cerebellum Interferes with Internal Representations of Sensory-Motor Information Related to Eye Movements in Humans. Cerebellum 2011; 10(4):711-9

Linea 7 – Diagnostica e terapia delle sindormi epilettiche

Brazzo D, Di Lorenzo G, Bill P, Fasce M, Papalia G, Veggiotti P, Seri S. Abnormal visual habituation in pediatric photosensitive epilepsy. Clin Neurophysiol 2011; 122(1): 16-20

Capovilla G, Beccaria F, Bianchi A, Canevini MP, Giordano L, Gobbi G, Mastrangelo M, Peruzzi C, Pisano T, Striano P, Veggiotti P, Vignoli A, Pruna D. Ictal EEG patterns in epilepsy with centro-temporal spikes. Brain Dev 2011; 33(4):301-9

Coppola G, Grosso S, Franzoni E, Veggiotti P, Zamponi N, Parisi P, Spalice A, Habetswallner F, Fels A, Verrotti A, D’Aniello A, Mangano S, Balestri A, Curatolo P, Pascotto A.Rufinamide in refractory childhood epileptic encephalopathies other than Lennox-Gastaut syndrome. Eur J Neurol  2011; 18(2):246-251

Verrotti A, Nanni G, Agostinelli S, Parisi P, Capovilla G, Beccaria F, Iannetti P, Spalice A, Coppola G, Franzoni E, Gentile V, Casellato S, Veggiotti P, Malgesini S, Crichiutti G, Balestri P, Grosso S, Zamponi N, Incorpora G, Savasta S, Costa P, Pruna D, Chiarelli F. Benign convulsions associated with mild gastroenteritis: A multicenter clinical study. Epilepsy Res 2011; 93(2-3):107-14

Moshé SL, Perucca E, Wiebe S, Mathern GW. The International League Against Epilepsy at the threshold of its second century: year 1. Epilepsia 2011; 52(1):185-7

Ragona F, Granata T, Bernardina BD, Offredi F, Darra F, Battaglia D, Morbi M, Brazzo D, Cappelletti S, Chieffo D, De Giorgi I, Fontana E, Freri E, Marini C, Toraldo A, Specchio N,Veggiotti P, Vigevano F, Guerrini R, Guzzetta F, Dravet C. Cognitive development in Dravet syndrome: A retrospective, multicenter study of 26 patients. Epilepsia 2011; 52(2):386-392

Freitas-Lima P, Alexandre V, Pereira LR, Feletti F, Perucca E, Sakamoto AC. Influence of enzyme inducing antiepileptic drugs on the pharmacokinetics of levetiracetam in patients with epilepsy. Epilepsy Res 2011; 94(1-2):117-20

Rheims S, Perucca E, Cucherat M, Ryvlin P. Factors determining response to antiepileptic drugs in randomized controlled trials. A systematic review and meta-analysis. Epilepsia 2011; 52(2):219-233

Prunetti P, Perucca E. New and forthcoming anti-epileptic drugs. Curr Opin Neurol 2011; 24(2):159-64

Fattore C, Boniver C, Capovilla G, Cerminara C, Citterio A, Coppola G, Costa P, Darra F, Vecchi M, Perucca E. A multicenter, randomized, placebo-controlled trial of levetiracetam in children and adolescents with newly diagnosed absence epilepsy. Epilepsia 2011; 52(4):802-9

Striano P, Belcastro V, Parisi P, Perucca P, Terzaghi M, Manni R. Status epilepticus migrainosus: Clinical, electrophysiologic, and imaging characteristics. Neurology 2011; 76(8):761

Alexandre V, Monteiro EA Jr, Freitas-Lima P, Pinto KD, Velasco TR, Terra VC, Pinheiro-Martins AP, Souza RM, Perucca E, Sakamoto AC. Addressing overtreatment in patients with refractory epilepsy at a tertiary referral centre in Brazil. Epileptic Disord 2011; 13(1):56-60

Citraro R, Scicchitano F, De Fazio S, Raggio R, Mainardi P, Perucca E, De Sarro G, Russo E. Preclinical activity profile of  -lactoalbumin, a whey protein rich in tryptophan, in rodent models of seizures and epilepsy. Epilepsy Res 2011; 95(1-2):60-9

Perucca E, Tomson T. The pharmacological treatment of epilepsy in adults. Lancet Neurol 2011;10(5): 446-56

Veggiotti P, Burlina A, Coppola G, Cusmai R, De Giorgis V, Guerrini R, Tagliabue A, Dalla Bernardina B. The ketogenic diet for Dravet syndrome and other epileptic encephalopathies: an Italian consensus. Epilepsia 2011; 52 Suppl 2(–):83-9

Manna I, Gambardella A, Bianchi A, Striano P, Tozzi R, Aguglia U, Beccaria F, Benna P, Campostrini R, Canevini MP, Condino F, Durisotti C, Elia M, Giallonardo AT, Iudice A, Labate A, La Neve A, Michelucci R, Muscas GC, Paravidino R, Zaccara G, Zucca C, Zara F, Perucca E. A functional polymorphism in the SCN1A gene does not influence antiepileptic drug responsiveness in Italian patients with focal epilepsy. Epilepsia 2011; 52(5):e40-e44

Mazzucchelli I, Rapetti M, Fattore C, Franco V, Gatti G, Perucca E. Development and validation of an HPLC-UV detection assay for the determination of rufinamide in human plasma and saliva. Anal Bioanal Chem 2011: 401(3):1013-21

Brodie M, Covanis T, Gil-Nagel A, Lerche H, Perucca E, Sills G, White S. Antiepileptic drug therapy: Does mechanism of action matter? Epilepsy Behav 2011; 21(4):331-41

Tomson T, Battino D, Bonizzoni E, Craig J, Lindhout D, Sabers A, Perucca E, Vajda F.Dose-dependent risk of malformations with antiepileptic drugs: an analysis of data from the EURAP epilepsy and pregnancy registry. Lancet Neurol 2011; 10(7): 609-17

Perucca E, Elger C, Halász P, Falcão A, Almeida L, Soares-da-Silva P. Pharmacokinetics of eslicarbazepine acetate at steady-state in adults with partial-onset seizures. Epilepsy Res 2011; 96(1-2):132-9

Perucca E. A young woman with recurring seizures. Neurosciences (Riyadh) 2011; 16(3):292-4

Tomson T, Battino D, Perucca E. Major birth defects after exposure to newer-generation antiepileptic drugs. JAMA 2011; 306(8):826-7; author reply 827

Perucca E. The pharmacology of new antiepileptic drugs: does a novel mechanism of action really matter? CNS Drugs 2011; 25(11):907-12

Fattore C, Perucca E. Novel medications for epilepsy. Drugs 2011; 71(16):2151-78

Rheims S, Perucca E, Ryvlin P. Clinical comparability of the new antiepileptic drugs in refractory partial epilepsy: Reply to Costa et al. Epilepsia 2011; 52(11):2139-41

Luoni C, Bisulli F, Canevini MP, De Sarro G, Fattore C, Galimberti CA, Gatti G, La Neve A, Muscas G, Specchio LM, Striano S, Perucca E. Determinants of health-related quality of life in pharmacoresistant epilepsy: Results from a large multicenter study of consecutively enrolled patients using validated quantitative assessments. Epilepsia 2011; 52(12):2181-91

Linea 9 – L’apporto della genetica alla definizione dei fenotipi clinici: patologie mono e poligeniche

Brunetti-Pierri N, Paciorkowski AR, Ciccone R, Mina ED, Bonaglia MC, Borgatti R, Schaaf CP, Sutton VR, Xia Z, Jelluma N, Ruivenkamp C, Bertrand M, de Ravel TJ, Jayakar P, Belli S, Rocchetti K, Pantaleoni C, D’Arrigo S, Hughes J, Cheung SW, Zuffardi O, Stankiewicz P.Duplications of FOXG1 in 14q12 are associated with developmental epilepsy, mental retardation, and severe speech impairment. Eur J Hum Genet 2011; 19(1):102-7

Vingolo EM, Di Fabio R, Salvatore S, Grieco G, Bertini E, Leuzzi V, Nesti C, Filla A, Tessa A, Pierelli F, Santorelli M, Casali C. Myelinated retinal fibers in autosomal recessive spastic ataxia of Charlevoix-Saguenay. Eur J Neurol 2011

van Bon BW, Balciuniene J, Fruhman G, Nagamani SC, Broome DL, Cameron E, Martinet D, Roulet E, Jacquemont S, Beckmann JS, Irons M, Potocki L, Lee B, Cheung SW, Patel A, Bellini M, Selicorni A, Ciccone R, Silengo M, Vetro A, Knoers NV, de Leeuw N, Pfundt R, Wolf B, Jira P, Aradhya S, Stankiewicz P, Brunner HG, Zuffardi O, Selleck SB, Lupski JR, de Vries BB.The phenotype of recurrent 10q22q23 deletions and duplications. Eur J Hum Genet 2011

Parodi F, Passoni L, Massimo L, Luksch R, Gambini C, Rossi E, Zuffardi O, Pistoia V, Pezzolo A. Identification of Novel Prognostic Markers in Relapsing Localized Resectable Neuroblastoma. OMICS 2011

Bui TH, Vetro A, Zuffardi O, Shaffer LG. Current controversies in prenatal diagnosis 3: is conventional chromosome analysis necessary in the post-array CGH era? Prenat Diagn 2011; 31(3):235-43

Caciotti A, Garman SC, Rivera-Colón Y, Procopio E, Catarzi S, Ferri L, Guido C, Martelli P, Parini R, Antuzzi D, Battini R, Sibilio M, Simonati A, Fontana E, Salviati A, Akinci G, Cereda C, Dionisi-Vici C, Deodato F, d’Amico A, d’Azzo A, Bertini E, Filocamo M, Scarpa M, di Rocco M, Tifft CJ, Ciani F, Gasperini S, Pasquini E, Guerrini R, Donati MA, Morrone A. GM1 gangliosidosis and Morquio B disease: An update on genetic alterations and clinical findings. Biochim Biophys Acta 2011; 1812(7):782-9

Vetro A, Ciccone R, Giorda R, Patricelli MG, Della Mina E, Forlino A, Zuffardi O. XX males SRY negative: a confirmed cause of infertility. J Med Genet 2011; 48(10):710-2

Bonaglia MC, Giorda R, Beri S, De Agostini C, Novara F, Fichera M, Grillo L, Galesi O, Vetro A, Ciccone R, Bonati MT, Giglio S, Guerrini R, Osimani S, Marelli S, Zucca C, Grasso R, Borgatti R, Mani E, Motta C, Molteni M, Romano C, Greco D, Reitano S, Baroncini A, Lapi E, Cecconi A, Arrigo G, Patricelli MG, Pantaleoni C, D’Arrigo S, Riva D, Sciacca F, Dalla Bernardina B, Zoccante L, Darra F, Termine C, Maserati E, Bigoni S, Priolo E, Bottani A, Gimelli S, Bena F, Brusco A, di Gregorio E, Bagnasco I, Giussani U, Nitsch L, Politi P, Martinez-Frias ML, Martínez-Fernández ML, Martínez Guardia N, Bremer A, Anderlid BM, Zuffardi O. Molecular Mechanisms Generating and Stabilizing Terminal 22q13 Deletions in 44 Subjects with Phelan/McDermid Syndrome. PLoS Genet 2011; 7(7):e1002173

Giorda R, Beri S, Bonaglia MC, Spaccini L, Scelsa B, Manolakos E, Mina ED, Ciccone R,Zuffardi O. Common structural features characterize interstitial intrachromosomal Xp and 18q triplications. Am J Med Genet A 2011; 155(11):2681-7

Tétreault M, Choquet K, Orcesi S, Tonduti D, Balottin U, Teichmann M, Fribourg S, Schiffmann R, Brais B, Vanderver A, Bernard G. Recessive Mutations in POLR3B, Encoding the Second Largest Subunit of Pol III, Cause a Rare Hypomyelinating Leukodystrophy.The Am J Hum Genet 2011; 89(5):652-5