Data / Ora
Date(s) - 06/02/2020
15:00 - 17:30


Research Seminar promosso dal BioData Science, IRCCS Fondazione Mondino (Pavia)

6 febbraio 2020 – Ore 15.00 – Aula Mondino (IRCCS Fondazione Mondino, via Mondino 2 – Pavia)

Bayesian modelling in the big data era: case studies in understanding neurodegenerative disease

Relatore: Kerrie Mengersen Distinguished Professor of Statistics, Queensland University of Technology (Brisbane, Australia)

Moderatore: Antonietta Mira, Università della Svizzera italiana e Università dell’Insubria


Il Seminario si svolgerà in lingua inglese

The so-called ‘big data era’ presents statisticians and data scientists with the opportunity to utilise a wide variety of data from different sources to learn about many complex problems. In this presentation, I will present some of the ways in which we have been developing various Bayesian hierarchical models and associated computational methods to improve understanding neurogedegenerative conditions such as Parkinson’s Disease (PD) and Alzheimer’s Disease (AD). The approaches include ensemble methods and mixed effects models to discover associations with PD, unsupervised clustering via mixture models to establish the likelihood of pre-clinical AD, and a probabilistic dynamic wombling model to simultaneously estimate brain covariance networks for AD patients.


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Presentazione K. Mengersen